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Reanalysis of Human Histone Methylation and Acetylation Patterns

Werner Van Belle1* - werner@yellowcouch.org, werner.van.belle@gmail.com

1- Department for Biosystems Science and Engineering; ETH Zurich; Mattenstrasse 24, Building 1058, Basel; Switzerland

Abstract :  We present a novel technique to analyze correlations between multiple sequencing tracks. This leads to a number of unique views on methylation patterns and through correlation maximization can we aggregate the information in a coherent manner. As last part of the talk we quickly introduce a normalization scheme that might improve correlation measures by adding noise.

Keywords:  deep sequencing correlation analysis normalization log values sqrt square root methylation acetylation
Reference:  Werner Van Belle; Reanalysis of Human Histone Methylation and Acetylation Patterns; Presented at Symposium on Next Generation Sequencing; University of Lausanne; Switzerland; January 2009
FilesUnil09.pdf, correlations.avi, alignment2profile.avi
See also:
The research article.
The browsable correlation maps between Histone Methylation and Acetylation tracks
Some posters [1, 2, 3]
Presentations of this research at FMI, Novartis, UNIL, University Zürich and ETH Zürich [1, 2]